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Updated November 15, 2026 · Clinician review in progress · How we write and review

How online weight-loss programs work

You fill out a health history, a licensed clinician reviews it, and if you qualify, a pharmacy ships your medication. A good program keeps checking in after that.

  1. Intake. You answer questions about your weight, health conditions, medications and goals. Be complete and honest; the clinician relies on it.
  2. Clinician review. A doctor, nurse practitioner or physician assistant licensed in your state reviews your history. Some programs require a video visit; others work by secure message.
  3. Labs. Many clinicians order blood work first, to check things like blood sugar, kidney function and thyroid.
  4. Prescription and pharmacy. If you qualify, the prescription goes to a pharmacy, which ships to you or holds it for pickup.
  5. Follow-up. Your clinician adjusts your dose over the first several months and watches for side effects.

Who usually qualifies

The FDA-approved weight-management drugs are generally indicated for adults with a BMI of 30 or more, or 27 or more with at least one weight-related condition such as high blood pressure or type 2 diabetes. Your clinician makes the final call.

Who usually doesn't

People who are pregnant or planning pregnancy, and people with a personal or family history of medullary thyroid cancer or MEN 2, are typically not candidates. Both Wegovy and Zepbound carry a boxed warning about thyroid C-cell tumors. Tell your clinician about any history of pancreatitis, gallbladder disease or kidney problems.

Common side effects

Nausea, diarrhea, vomiting and constipation are the most common, especially when the dose increases. Contact your clinician about severe stomach pain, which can signal pancreatitis or gallbladder problems.

If you are told you're not a candidate, that's the system working. Be wary of any program that approves everyone.